Elastic, Viscoelastic, and Fracture Properties of Bone Tissue Measured by Nanoindentation

Abstract

Nanoindentation is a sophisticated technique that has been used to characterize a wide selection of materials, including bone. Given the complex and hierarchical nature of bone, nanoindentation allows for assessment of composite material properties at the nano-range of bone tissue. These nanoindentation-based measures can provide important baseline information to aid in understanding the overall mechanical behavior, the pathologic changes of disease, and the pharmaceutical response of bone. In this review, the challenges and limitations of our current knowledge related to nanoindentation are presented as well as the future directions for its application to bone biology.

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Title
Elastic, Viscoelastic, and Fracture Properties of Bone Tissue Measured by Nanoindentation
Book Title
Handbook of Nanomaterials Properties
Book DOI
10.1007/978-3-642-31107-9
Chapter DOI
10.1007/978-3-642-31107-9_46
Part of
Volume
Editors
  • Bharat Bhushan Send Email (1)
  • Dan Luo Send Email (2)
  • Scott R. Schricker Send Email (3)
  • Wolfgang Sigmund Send Email (4)
  • Stefan Zauscher Send Email (5)
  • Editor Affiliation
  • 1 Nanoprobe Laboratory for Bio- & Nanotechnology and Biomimetics, Ohio State University, Columbus, Ohio, USA
  • 2 Department of Biological and Environmental Engineering, Cornell University, Ithaca, New York, USA
  • 3 Division of Restorative, Prosthetic and Primary Care, The Ohio State University, College of Dentistry, Columbus, Ohio, USA
  • 4 Department of Materials Science and Engineering, University of Florida, Gainesville, Florida, USA
  • 5 Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina, USA
  • Authors
  • Do-Gyoon Kim Send Email (6)
  • Kathy L. Elias Send Email (6)
  • Author Affiliation
  • 6 Division of Orthodontics, College of Dentistry, The Ohio State University, 4088 Postle Hall, 305W. 12th Ave, 43210-1267, Columbus, OH, USA
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