Porous Structures from Biobased Synthetic Polymers via Freeze-Drying

Abstract

Materials containing porous structures, which have been intensively studied for decades, play an important role in medical implantation (synthetic blood vessels, skin, drug delivery, bone and cartilage reconstruction, tissue engineering application, periodontal repair, etc.) and other variety of applications in our lives. The development of porous structures with interpore connections of adequate diameter as well as strength has long been expected as an ideal implant substitute. The presence of pores in the materials used for medical applications allows migration and proliferation of osteoblasts and mesenchymal cells, as well as their vascularization. Pore surface also improves mechanical interlocking between implant biomaterials and surrounding natural bones, providing greater mechanical stability at this critical interface. Porous structures can be produced with different techniques, namely fiber bonding, gas foaming/particulate leaching, phase separation, high pressure processing, electrospinning and rapid prototyping, and freeze-drying. Every technique has advantages and disadvantages. This chapter mainly deals with the manufacturing of porous structures from biobased synthetic polymers using freeze-drying approach and its modified techniques.

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Title
Porous Structures from Biobased Synthetic Polymers via Freeze-Drying
Book Title
Porous lightweight composites reinforced with fibrous structures
Book DOI
10.1007/978-3-662-53804-3
Chapter DOI
10.1007/978-3-662-53804-3_8
Part of
Volume
Editors
  • Yiqi Yang Send Email (1)
  • Jianyong Yu Send Email (2)
  • Helan Xu Send Email (3)
  • Baozhong Sun Send Email (4)
  • Editor Affiliation
  • 1 Department of Textiles, Merchandising and Fashion Design, University of Nebraska-Lincoln, Lincoln, Nebraska, USA
  • 2 College of Textiles, Donghua University, Shanghai, China
  • 3 Department of Textiles, Merchandising and Fashion Design, University of Nebraska-Lincoln, Lincoln, Nebraska, USA
  • 4 College of Textiles, Donghua University, Shanghai, China
  • Authors
  • M. Fazley Elahi (5)
  • Fujun Wang (5)
  • Yan Li (5)
  • Lu Wang Send Email (5)
  • Author Affiliation
  • 5 Key Laboratory of Textile Science and Technology of Ministry of Education, College of Textiles, Donghua University, College Building #3, 2999 North Renmin Road, Songjiang District, Shanghai, 201620, China
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